SLC23A1
Identifiers
AliasesSLC23A1, SLC23A2, SVCT1, YSPL3, solute carrier family 23 member 1
External IDsOMIM: 603790 MGI: 1341903 HomoloGene: 40769 GeneCards: SLC23A1
Orthologs
SpeciesHumanMouse
Entrez

9963

20522

Ensembl

ENSG00000170482

ENSMUSG00000024354

UniProt

Q9UHI7

Q9Z2J0

RefSeq (mRNA)

NM_005847
NM_152685

NM_011397

RefSeq (protein)

NP_005838
NP_689898

NP_035527

Location (UCSC)Chr 5: 139.37 – 139.38 MbChr 18: 35.75 – 35.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Solute carrier family 23 member 1 is a protein that in humans is encoded by the SLC23A1 gene.[5][6][7]

Function

The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2.[7]

See also

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000170482 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024354 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Faaland CA, Race JE, Ricken G, Warner FJ, Williams WJ, Holtzman EJ (November 1998). "Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase transporters". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1442 (2–3): 353–60. doi:10.1016/S0167-4781(98)00151-1. PMID 9804989.
  6. Tsukaguchi H, Tokui T, Mackenzie B, Berger UV, Chen XZ, Wang Y, Brubaker RF, Hediger MA (May 1999). "A family of mammalian Na+-dependent L-ascorbic acid transporters". Nature. 399 (6731): 70–5. Bibcode:1999Natur.399...70T. doi:10.1038/19986. PMID 10331392. S2CID 4425479.
  7. 1 2 "Entrez Gene: SLC23A1 solute carrier family 23 (nucleobase transporters), member 1".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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