SEMA3E
Identifiers
AliasesSEMA3E, M-SEMAH, M-SemaK, SEMAH, coll-5, semaphorin 3E
External IDsOMIM: 608166 MGI: 1340034 HomoloGene: 8247 GeneCards: SEMA3E
Orthologs
SpeciesHumanMouse
Entrez

9723

20349

Ensembl

n/a

ENSMUSG00000063531

UniProt

O15041

P70275

RefSeq (mRNA)

NM_001178129
NM_012431

NM_011348

RefSeq (protein)

NP_001171600
NP_036563

NP_035478

Location (UCSC)n/aChr 5: 14.08 – 14.31 Mb
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Semaphorin 3E is a protein that in humans is encoded by the SEMA3E gene. [4]

Function

Semaphorin are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins.

This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010].

References

  1. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000063531 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Entrez Gene: Semaphorin 3E". Retrieved 2018-04-26.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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