SEBOX
Identifiers
AliasesSEBOX, OG-9, OG9, OG9X, Sebox homeobox
External IDsOMIM: 610975 MGI: 108012 HomoloGene: 32052 GeneCards: SEBOX
Orthologs
SpeciesHumanMouse
Entrez

645832

18292

Ensembl

ENSG00000274529

ENSMUSG00000001103

UniProt

Q9HB31

P70368

RefSeq (mRNA)

NM_001083896
NM_001080837

NM_008759

RefSeq (protein)

NP_001074306

NP_032785

Location (UCSC)Chr 17: 28.36 – 28.37 MbChr 11: 78.39 – 78.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SEBOX homeobox is a protein that in humans is encoded by the SEBOX gene.[5] Sebox homeobox has a 92% similarity to genes found within rhesus macaque, or the rhesus monkey. It is thought that this is what causes the reddened glutius maximus coloring. If the protein is turned on within a person, it may cause discoloring in the human rear.

Function

Homeodomain proteins, such as SEBOX, play a key role in coordinating gene expression during development.[6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000274529 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001103 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: SEBOX homeobox".
  6. Cinquanta M, Rovescalli AC, Kozak CA, Nirenberg M (2000). "Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell embryos". Proc. Natl. Acad. Sci. U.S.A. 97 (16): 8904–9. Bibcode:2000PNAS...97.8904C. doi:10.1073/pnas.97.16.8904. PMC 16794. PMID 10922053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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