SH3BP5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSH3BP5, SAB, SH3BP-5, SH3 domain binding protein 5
External IDsOMIM: 605612 MGI: 1344391 HomoloGene: 23450 GeneCards: SH3BP5
Orthologs
SpeciesHumanMouse
Entrez

9467

24056

Ensembl

ENSG00000131370

ENSMUSG00000021892

UniProt

O60239

Q9Z131

RefSeq (mRNA)

NM_001018009
NM_004844

NM_011894
NM_001347585

RefSeq (protein)

NP_001018009
NP_004835

Location (UCSC)Chr 3: 15.25 – 15.34 MbChr 14: 31.08 – 31.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SH3 domain-binding protein 5 is a protein that in humans is encoded by the SH3BP5 gene.[5][6][7]

Interactions

SH3BP5 has been shown to interact with Bruton's tyrosine kinase[5][6] and MAPK8.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000131370 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021892 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Matsushita M, Yamadori T, Kato S, Takemoto Y, Inazawa J, Baba Y, et al. (April 1998). "Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (BtK)". Biochemical and Biophysical Research Communications. 245 (2): 337–343. doi:10.1006/bbrc.1998.8420. PMID 9571151.
  6. 1 2 Yamadori T, Baba Y, Matsushita M, Hashimoto S, Kurosaki M, Kurosaki T, et al. (May 1999). "Bruton's tyrosine kinase activity is negatively regulated by Sab, the Btk-SH3 domain-binding protein". Proceedings of the National Academy of Sciences of the United States of America. 96 (11): 6341–6346. Bibcode:1999PNAS...96.6341Y. doi:10.1073/pnas.96.11.6341. PMC 26883. PMID 10339589.
  7. "Entrez Gene: SH3BP5 SH3-domain binding protein 5 (BTK-associated)".
  8. Wiltshire C, Matsushita M, Tsukada S, Gillespie DA, May GH (November 2002). "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria". The Biochemical Journal. 367 (Pt 3): 577–585. doi:10.1042/BJ20020553. PMC 1222945. PMID 12167088.

Further reading a

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