P3H4
Identifiers
AliasesP3H4, NO55, NOL55, SC65, LEPREL4, prolyl 3-hydroxylase family member 4 (non-enzymatic), prolyl 3-hydroxylase family member 4 (inactive)
External IDsOMIM: 617419 MGI: 1913430 HomoloGene: 4713 GeneCards: P3H4
Orthologs
SpeciesHumanMouse
Entrez

10609

66180

Ensembl

ENSG00000141696

ENSMUSG00000006931

UniProt

Q92791

Q8K2B0

RefSeq (mRNA)

NM_006455

NM_176830
NM_001378981

RefSeq (protein)

NP_006446

NP_789800
NP_001365910

Location (UCSC)Chr 17: 41.8 – 41.81 MbChr 11: 100.3 – 100.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptonemal complex protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded by the LEPREL4 gene.[5]

Function

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141696 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000006931 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: SC65 synaptonemal complex protein SC65".

Further reading


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.