PharmVar
Content
DescriptionThe PharmVar Consortium
Data types
captured
Pharmacogenomics and Pharmacogenetics
OrganismsHuman
Contact
Research centerChildren's Mercy Hospital
Primary citationPMID 29134625
Release date2017
Access
Websitewww.pharmvar.org
Download URLwww.pharmvar.org/download
Web service URLwww.pharmvar.org/documentation
Miscellaneous
Curation policyYes

Pharmacogene Variation Consortium (abbreviated as PhamVar) is an international group of experts that maintains a systematic nomenclature system for allelic variations of genes that affect the metabolism of drugs.[1][2]

The database is focused on cytochrome P450 enzymes, but is being expanded into other classes of enzymes. The original nomenclature was maintained by the Human CYP Allele Nomenclature Database. However PhamVar took over this function in 2017.[3]

See also

References

  1. Gaedigk A, Ingelman-Sundberg M, Miller NA, Leeder JS, Whirl-Carrillo M, Klein TE (March 2018). "The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database". Clinical Pharmacology and Therapeutics. 103 (3): 399–401. doi:10.1002/cpt.910. PMC 5836850. PMID 29134625.
  2. Gaedigk A, Sangkuhl K, Whirl-Carrillo M, Twist GP, Klein TE, Miller NA (January 2019). "The Evolution of PharmVar". Clinical Pharmacology and Therapeutics. 105 (1): 29–32. doi:10.1002/cpt.1275. PMC 6312487. PMID 30536702.
  3. Tornio A, Backman JT (2018). "Cytochrome P450 in Pharmacogenetics: An Update". Pharmacogenetics. Advances in Pharmacology. Vol. 83. San Diego, Calif. pp. 3–32. doi:10.1016/bs.apha.2018.04.007. hdl:10138/300396. ISBN 9780128133811. PMID 29801580.{{cite book}}: CS1 maint: location missing publisher (link)
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