NXF2
Identifiers
AliasesNXF2, CT39, TAPL-2, TCP11X2, nuclear RNA export factor 2
External IDsOMIM: 300315 MGI: 1933192 HomoloGene: 88604 GeneCards: NXF2
Orthologs
SpeciesHumanMouse
Entrez

56001

83454

Ensembl

ENSG00000269405

ENSMUSG00000009941

UniProt

Q9GZY0

n/a

RefSeq (mRNA)

NM_022053
NM_001039910
NM_017809

NM_001289735
NM_001289736
NM_031259

RefSeq (protein)

NP_071336
NP_001093156

n/a

Location (UCSC)Chr X: 102.25 – 102.33 MbChr X: 133.85 – 133.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nuclear RNA export factor 2 is a protein that in humans is encoded by the NXF2 gene.[5][6][7]

Function

This gene is one of a family of nuclear RNA export factor genes. It encodes a protein that is involved in mRNA export, is located in the nucleoplasm, and is associated with the nuclear envelope. Alternative splicing seems to be a common mechanism in this gene family. Two variants have been found for this gene.[7]

Interactions

NXF2 has been shown to interact with NUP214.[5]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000269405 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009941 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 Herold A, Suyama M, Rodrigues JP, Braun IC, Kutay U, Carmo-Fonseca M, Bork P, Izaurralde E (Dec 2000). "TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture". Molecular and Cellular Biology. 20 (23): 8996–9008. doi:10.1128/MCB.20.23.8996-9008.2000. PMC 86553. PMID 11073998.
  6. Wang PJ, McCarrey JR, Yang F, Page DC (Apr 2001). "An abundance of X-linked genes expressed in spermatogonia". Nature Genetics. 27 (4): 422–426. doi:10.1038/86927. PMID 11279525. S2CID 14200121.
  7. 1 2 "Entrez Gene: NXF2 nuclear RNA export factor 2".

Further reading


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