NPAT
Identifiers
AliasesNPAT, E14, E14/p220, nuclear protein, co-activator of histone transcription, nuclear protein, coactivator of histone transcription
External IDsOMIM: 601448 MGI: 107605 HomoloGene: 1888 GeneCards: NPAT
Orthologs
SpeciesHumanMouse
Entrez

4863

244879

Ensembl

ENSG00000149308

ENSMUSG00000033054

UniProt

Q14207

Q8BMA5

RefSeq (mRNA)

NM_002519
NM_001321307

NM_001081152
NM_178905

RefSeq (protein)

NP_001308236
NP_002510

NP_001074621

Location (UCSC)Chr 11: 108.16 – 108.22 MbChr 9: 53.45 – 53.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein NPAT also known as nuclear protein of the ATM locus is a protein that in humans is encoded by the NPAT gene.[5][6]

Interactions

NPAT (gene) has been shown to interact with Glyceraldehyde 3-phosphate dehydrogenase[7] and POU2F1.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000149308 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033054 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Imai T, Sugawara T, Nishiyama A, Shimada R, Ohki R, Seki N, Sagara M, Ito H, Yamauchi M, Hori T (Jun 1997). "The structure and organization of the human NPAT gene". Genomics. 42 (3): 388–92. doi:10.1006/geno.1997.4769. PMID 9205109.
  6. "Entrez Gene: NPAT nuclear protein, ataxia-telangiectasia locus".
  7. 1 2 Zheng L, Roeder RG, Luo Y (Jul 2003). "S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component". Cell. 114 (2): 255–66. doi:10.1016/S0092-8674(03)00552-X. PMID 12887926. S2CID 5543647.

Further reading

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