MINPP1
Identifiers
AliasesMINPP1, HIPER1, MINPP2, MIPP, multiple inositol-polyphosphate phosphatase 1, PCH16
External IDsOMIM: 605391 MGI: 1336159 HomoloGene: 37980 GeneCards: MINPP1
EC number3.1.3.80
Orthologs
SpeciesHumanMouse
Entrez

9562

17330

Ensembl

ENSG00000107789

ENSMUSG00000024896

UniProt

Q9UNW1

Q9Z2L6

RefSeq (mRNA)

NM_001178117
NM_001178118
NM_004897

NM_010799

RefSeq (protein)

NP_001171588
NP_001171589
NP_004888

NP_034929

Location (UCSC)Chr 10: 87.5 – 87.55 MbChr 19: 32.46 – 32.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Multiple inositol polyphosphate phosphatase 1 is an enzyme that in humans is encoded by the MINPP1 gene.[5][6]

MINPP1 hydrolyzes the abundant metabolites inositol pentakisphosphate and inositol hexakisphosphate and, like PTEN (MIM 601728), has the ability to remove 3-phosphate from inositol phosphate substrates.[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000107789 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024896 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chi H, Tiller GE, Dasouki MJ, Romano PR, Wang J, O'keefe RJ, Puzas JE, Rosier RN, Reynolds PR (May 1999). "Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19". Genomics. 56 (3): 324–36. doi:10.1006/geno.1998.5736. PMID 10087200.
  6. 1 2 "Entrez Gene: MINPP1 multiple inositol polyphosphate histidine phosphatase, 1".

Further reading


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