MED18
Identifiers
AliasesMED18, p28b, mediator complex subunit 18, SRB5
External IDsOMIM: 612384 MGI: 1914469 HomoloGene: 9756 GeneCards: MED18
Orthologs
SpeciesHumanMouse
Entrez

54797

67219

Ensembl

ENSG00000130772
ENSG00000284944

ENSMUSG00000066042

UniProt

Q9BUE0

Q9CZ82

RefSeq (mRNA)

NM_001127350
NM_017638

NM_026039

RefSeq (protein)

NP_001120822
NP_060108

NP_080315

Location (UCSC)Chr 1: 28.33 – 28.34 MbChr 4: 132.19 – 132.19 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Mediator complex subunit 18 (Med18) is a protein that in humans is encoded by the MED18 gene.[5]

Function

Med18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.[6]

See also

References

  1. 1 2 3 ENSG00000284944 GRCh38: Ensembl release 89: ENSG00000130772, ENSG00000284944 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000066042 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Mediator complex subunit 18".
  6. Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, et al. (April 2003). "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". The Journal of Biological Chemistry. American Society for Biochemistry & Molecular Biology (ASBMB). 278 (17): 15123–7. doi:10.1074/jbc.c300054200. PMID 12584197.

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