In biology, homotopic connectivity is the connectivity between mirror areas of the human brain hemispheres.[1]

Changes in the homotopic connectivity are to disorders such as melancholic depression,[2] major depressive disorder,[3] schizophrenia[4] and cortical seizures.[5]

References

  1. Mancuso L, Costa T, Nani A, Manuello J, Liloia D, Gelmini G, et al. (March 2019). "The homotopic connectivity of the functional brain: a meta-analytic approach". Scientific Reports. 9 (1): 3346. Bibcode:2019NatSR...9.3346M. doi:10.1038/s41598-019-40188-3. PMC 6399443. PMID 30833662.
  2. Shan X, Cui X, Liu F, Li H, Huang R, Tang Y, et al. (May 2021). "Shared and distinct homotopic connectivity changes in melancholic and non-melancholic depression". Journal of Affective Disorders. 287: 268–275. doi:10.1016/j.jad.2021.03.038. PMID 33799047. S2CID 232775109.
  3. Hermesdorf M, Sundermann B, Feder S, Schwindt W, Minnerup J, Arolt V, et al. (March 2016). "Major depressive disorder: Findings of reduced homotopic connectivity and investigation of underlying structural mechanisms". Human Brain Mapping. 37 (3): 1209–1217. doi:10.1002/hbm.23097. PMC 6867499. PMID 26704348.
  4. Li HJ, Xu Y, Zhang KR, Hoptman MJ, Zuo XN (April 2015). "Homotopic connectivity in drug-naïve, first-episode, early-onset schizophrenia". Journal of Child Psychology and Psychiatry, and Allied Disciplines. 56 (4): 432–443. doi:10.1111/jcpp.12307. PMC 4333112. PMID 25130214.
  5. Rossi LF, Wykes RC, Kullmann DM, Carandini M (August 2017). "Focal cortical seizures start as standing waves and propagate respecting homotopic connectivity". Nature Communications. 8 (1): 217. Bibcode:2017NatCo...8..217R. doi:10.1038/s41467-017-00159-6. PMC 5550430. PMID 28794407.


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