major histocompatibility complex (human), class I, B56
Alleles B*5601, *5602, *5603, *5604
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*5601
B*5602
B*5603
B*5604
Locus chr.6 6p21.31

HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)

Serotype

B56 and B22 serotype recognition of Some HLA B*56 allele-group gene products[2]
B*56B56 B22Sample
allele % %size (N)
5601725671
560346813
56047311

Allele distribution

HLA B*5601 frequencies
freq
ref.Population(%)
[3]Australian Aborigine Kimberly35.5
[3]Papua New Guinea Madang34.6
[3]Papua New Guinea New Britain Rabaul31.6
[3]Taiwan Ami20.4
[3]New Caledonia19.2
[3]Australian Aborigine Groote Eylandt18.0
[3]Australian Aborigine Cape York Peninsula16.5
[3]Australian Aborigine Yuendumu11.4
[3]China Yunnan Lisu9.4
[3]China Yunnan Nu3.8
[3]Senegal Niokholo Mandenka2.7
[3]Sudanese2.5
[3]American Samoa2.0
[3]China Guangxi Maonan1.9
[3]Taiwan Hakka1.8
[3]Thailand1.8
[3]Finland1.7
[3]Georgia Tbilisi Kurds1.7
[3]India Andhra Pradesh Golla1.4
[3]Croatia1.3
[3]Japan (5)1.3
[3]South Africa Natal Tamil1.0
[3]Taiwan Rukai1.0

References

  1. Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
  2. derived from IMGT/HLA
  3. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
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