GGT7
Identifiers
AliasesGGT7, D20S101, GGT4, GGTL3, GGTL5, dJ18C9.2, gamma-glutamyltransferase 7
External IDsOMIM: 612342 MGI: 1913385 HomoloGene: 70866 GeneCards: GGT7
EC number3.4.19.13
Orthologs
SpeciesHumanMouse
Entrez

2686

207182

Ensembl

ENSG00000131067

ENSMUSG00000027603

UniProt

Q9UJ14

Q99JP7

RefSeq (mRNA)

NM_178026
NM_001351702
NM_178025

NM_144786
NM_001362898
NM_001362900

RefSeq (protein)

NP_821158
NP_001338631
NP_821158.2

NP_659035
NP_001349827
NP_001349829

Location (UCSC)Chr 20: 34.84 – 34.87 MbChr 2: 155.49 – 155.52 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7 gene.[5][6][7]

Function

Gamma-glutamyltransferase is a membrane-associated protein involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.[7]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000131067 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027603 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA (August 1993). "Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes". Genomics. 17 (2): 299–305. doi:10.1006/geno.1993.1325. PMID 8104871.
  6. Heisterkamp N, Groffen J, Warburton D, Sneddon TP (May 2008). "The human gamma-glutamyltransferase gene family". Human Genetics. 123 (4): 321–32. doi:10.1007/s00439-008-0487-7. PMID 18357469. S2CID 15916758.
  7. 1 2 "Entrez Gene: GGTL3 gamma-glutamyltransferase-like 3".

Further reading

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