GPHA2
Identifiers
AliasesGPHA2, A2, GPA2, ZSIG51, glycoprotein hormone alpha 2, glycoprotein hormone subunit alpha 2
External IDsOMIM: 609651 MGI: 2156541 HomoloGene: 15605 GeneCards: GPHA2
Orthologs
SpeciesHumanMouse
Entrez

170589

170458

Ensembl

ENSG00000149735

ENSMUSG00000024784

UniProt

Q96T91

Q925Q5

RefSeq (mRNA)

NM_130769

NM_130453

RefSeq (protein)

NP_570125

NP_569720

Location (UCSC)Chr 11: 64.93 – 64.94 MbChr 19: 6.28 – 6.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Glycoprotein hormone alpha-2 is a protein that in humans is encoded by the GPHA2 gene.[5][6]

GPHA2 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002).[supplied by OMIM][6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000149735 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024784 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Hsu SY, Nakabayashi K, Nishi S, Kumagai J, Kudo M, Sherwood OD, Hsueh AJ (Jan 2002). "Activation of orphan receptors by the hormone relaxin". Science. 295 (5555): 671–4. Bibcode:2002Sci...295..671H. doi:10.1126/science.1065654. PMID 11809971. S2CID 32693420.
  6. 1 2 "Entrez Gene: GPHA2 glycoprotein hormone alpha 2".

7. Z. Gong, W. Wang, K. El Omari, A. A. Lebedev, O. B. Clarke, W. A. Hendrickson, Crystal structure of LGR ligand alpha2/beta5 from Caenorhabditis elegans with implications for the evolution of glycoprotein hormones. Proc Natl Acad Sci U S A 120 (1), e2218630120 (2023). https://www.pnas.org/doi/10.1073/pnas.2218630120#

Further reading


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