G3BP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesG3BP2, G3BP stress granule assembly factor 2
External IDsMGI: 2442040 HomoloGene: 137244 GeneCards: G3BP2
Orthologs
SpeciesHumanMouse
Entrez

9908

23881

Ensembl

ENSG00000138757

ENSMUSG00000029405

UniProt

Q9UN86

P97379

RefSeq (mRNA)

NM_012297
NM_203504
NM_203505

RefSeq (protein)

NP_036429
NP_987100
NP_987101
NP_987100.1

Location (UCSC)Chr 4: 75.64 – 75.72 MbChr 5: 92.2 – 92.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.[5][6][7]


Interactions

G3BP2 has been shown to interact with IκBα.[8]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000138757 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029405 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, et al. (June 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
  6. Kennedy D, Wood SA, Ramsdale T, Tam PP, Steiner KA, Mattick JS (June 1998). "Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif". Biomedical Peptides, Proteins & Nucleic Acids. 2 (3): 93–9. PMID 9575347.
  7. "Entrez Gene: G3BP2 GTPase activating protein (SH3 domain) binding protein 2".
  8. Prigent M, Barlat I, Langen H, Dargemont C (November 2000). "IkappaBalpha and IkappaBalpha /NF-kappa B complexes are retained in the cytoplasm through interaction with a novel partner, RasGAP SH3-binding protein 2". The Journal of Biological Chemistry. 275 (46): 36441–9. doi:10.1074/jbc.M004751200. PMID 10969074.

Further reading


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