| THEMIS2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | THEMIS2, C1orf38, ICB-1, thymocyte selection associated family member 2, ICB1, Chromosome 1 open reading frame 38 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 617856 MGI: 2446213 HomoloGene: 21009 GeneCards: THEMIS2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Chromosome 1 open reading frame 38 is a protein that in humans is encoded by the C1orf38 gene.[5] The gene is also known as ICB-1 and THEMIS2 in humans, and the orthologue in mice is BC013712.[5] C1orf38 has been associated with cancer susceptibility.[6]
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000130775 - Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037731 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 "Chromosome 1 open reading frame 38". Retrieved 2011-12-07.
- ↑ Springwald, A.; Lattrich, C.; Seitz, S.; Ortmann, O.; Treeck, O. (2009). "Single Nucleotide Polymorphisms in Human Gene icb-1 and Breast Cancer Susceptibility". Cancer Investigation. 27 (6): 669–672. doi:10.1080/07357900802620877. PMID 19308812. S2CID 205570175.
Further reading
- Treeck, O.; Springwald, A.; Konwisorz, A.; Lattrich, C.; Goerse, R.; Ortmann, O.; Treeck, O. (2011). "Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells". International Journal of Molecular Medicine. 28 (1): 121–127. doi:10.3892/ijmm.2011.663. PMID 21455565.
- Springwald, A.; Lattrich, C.; Skrzypczak, M.; Goerse, R.; Ortmann, O.; Treeck, O. (2010). "Icb-1Gene Expression is Elevated in Human Endometrial Adenocarcinoma and is Closely Associated with HER2 Expression". Cancer Investigation. 28 (9): 904–909. doi:10.3109/07357907.2010.483511. PMID 20569072. S2CID 35017943.
- Konwisorz, A.; Springwald, A.; Haselberger, M.; Goerse, R.; Ortmann, O.; Treeck, O. (2009). "Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells". Endocrine-Related Cancer. 17 (1): 147–157. doi:10.1677/ERC-09-0095. PMID 19942713.
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