ARCN1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesARCN1, COPD, archain 1, SRMMD
External IDsOMIM: 600820 MGI: 2387591 HomoloGene: 1250 GeneCards: ARCN1
Orthologs
SpeciesHumanMouse
Entrez

372

213827

Ensembl

ENSG00000095139

ENSMUSG00000032096

UniProt

P48444

Q5XJY5

RefSeq (mRNA)

NM_001142281
NM_001655

NM_145985

RefSeq (protein)

NP_001135753
NP_001646

NP_666097

Location (UCSC)Chr 11: 118.57 – 118.6 MbChr 9: 44.65 – 44.68 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Archain 1 is a protein that in humans is encoded by the ARCN1 gene. [5]

Function

This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein. Archain sequences are well conserved among eukaryotes and this protein may play a fundamental role in eukaryotic cell biology. It has similarities to heat shock proteins and clathrin-associated proteins, and may be involved in vesicle structure or vesicle trafficking.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000095139 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032096 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Archain 1". Retrieved 2016-06-22.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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