Meclocycline
Skeletal formula of meclocycline
Ball-and-stick model of the meclocycline molecule
Clinical data
AHFS/Drugs.comMicromedex Detailed Consumer Information
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • (2E,4S,4aR,5S,5aR,12aS)-2-[Amino(hydroxy)methylene]-7-chloro-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methylene-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.016.309
Chemical and physical data
FormulaC22H21ClN2O8
Molar mass476.87 g·mol−1
3D model (JSmol)
  • CN(C)[C@H]1[C@@H]2[C@H]([C@@H]3C(=C)C4=C(C=CC(=C4C(=O)C3=C([C@@]2(C(=O)C(=C1O)C(=O)N)O)O)O)Cl)O
  • InChI=1S/C22H21ClN2O8/c1-6-9-7(23)4-5-8(26)11(9)16(27)12-10(6)17(28)14-15(25(2)3)18(29)13(21(24)32)20(31)22(14,33)19(12)30/h4-5,10,14-15,17,26,28-30,33H,1H2,2-3H3,(H2,24,32)/t10-,14-,15+,17+,22+/m1/s1 ☒N
  • Key:GGQJXCQBBONZFX-IWVLMIASSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Meclocycline (INN) is a tetracycline antibiotic.[1] It is used topically (i.e. for skin infections) as it is totally insoluble in water and may cause liver and kidney damage if given systemically.

Its production for medical use has been discontinued.[2] It was previously sold in the United States by Pfizer under the brand name Meclan.[3]

References

  1. ↑ "Meclocycline sulfosalicylate". pubchem.ncbi.nlm.nih.gov. Retrieved 3 January 2019.
  2. ↑ "Orange Book: Approved Drug Products with Therapeutic Equivalence Evaluations". www.accessdata.fda.gov. Retrieved 3 January 2019.
  3. ↑ "MECLAN Drugs@FDA: FDA-Approved Drugs". www.accessdata.fda.gov. United States Food and Drug Administration. 11 August 2022. Retrieved 2022-08-11.
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