This is a list of United States federal agencies that are primarily devoted to research and development, including their notable subdivisions. These agencies are responsible for carrying out the science policy of the United States.
Independent agencies
- National Science Foundation (NSF)
- National Aeronautics and Space Administration (NASA)
- Environmental Protection Agency Office of Research and Development
- Intelligence Advanced Research Projects Activity (IARPA)
- Smithsonian Institution research centers and programs
Department of Agriculture
Department of Commerce
Department of Defense
- Defense Advanced Research Projects Agency (DARPA)
- Uniformed Services University of the Health Sciences (USU)
Department of the Air Force
- Air Force Research Laboratory (AFRL)
- Air Force Life Cycle Management Center (AFLCMC)
- Air Force Nuclear Weapons Center (NWC)
- Air Force Institute of Technology (AFIT)
- Space Systems Command (SSC)
Department of the Army
Department of the Navy
- Marine Corps Combat Development Command (MCCDC)
- Office of Naval Research (ONR)
- Naval Research Laboratory (NRL)
- Bureau of Medicine and Surgery (BUMED)
- Naval Air Warfare Center (NASC)
- Naval Surface Warfare Center (NSWC)
- Naval Undersea Warfare Center (NUWC)
- Naval Command, Control and Ocean Surveillance Warfare Center (NCCOSC)
- Naval Postgraduate School (NPS)
- Naval Air Weapons Station China Lake (NAWSCL)
- United States Naval Observatory (USNO)
Department of Education
Department of Energy
- Office of Science (DOE SC)
- Advanced Research Projects Agency-Energy (ARPA-E)
- National Laboratories
Department of Health and Human Services
Department of Homeland Security
Department of the Interior
Department of Justice
Department of Transportation
- Research and Innovative Technology Administration
- Federal Aviation Administration Research, Engineering, and Development
- Federal Highway Administration Research and Technology
Environmental Protection Agency
- Air Research
- Water Research
- Climate Change Research
- Ecosystems Research
- Land, Oil Spill, and Waste Management Research
- Homeland Security Research
Veterans Affairs
Multi-agency initiatives
Judicial branch
Legislative branch
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