Vitamin B₁₂ is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.

B12 or B-12 may also refer to:

Music

• B12 (band), a British electronic music duo
• "B12", a song by Grey Daze led by Chester Bennington
• "B12", a song by Lil Durk from Almost Healed

Transportation

• B12 (New York City bus), a bus line serving Brooklyn
• Bensen B-12, a 1961 American unconventional aircraft
• Chery B12, a 2007 Chinese Chery automobile model
• LNER Class B12, a class of steam locomotives
• Mallee Highway or B12
• Martin B-12, a modified version of the Martin B-10 bomber
• Nissan Sunny B12, a car model
• Queensland B12 class locomotive, a class of steam railway locomotive
• Alpina B12, a car model by Alpina

Other uses

• Brandon C. Rodegeb or B-12 (born 1977), American music executive, film-maker, rap artist, and writer
• Caro–Kann Defence's ECO code in chess
• B12, a student model clarinet manufactured by Buffet Crampon
• Boron-12 (B-12 or ¹²B), an isotope of boron
• Big 12 Conference

See also

• HLA-B12, an HLA-B serotype
• IgG1-b12, an antibody against the HIV surface protein gp120 found in some long-term nonprogressors
• 12B (disambiguation)